Analytical Chemistry

Perdita Barran

University of Manchester

Perdita Barran holds a Chair of Mass Spectrometry in the Department of Chemistry, is Associate Dean for Research Facilities and Director of the Michael Barber Centre for Collaborative Mass Spectrometry at the Manchester Institute of Biotechnology, The University of Manchester, UK. She develops and applies ion-mobility spectrometry–mass spectrometry to the study of molecule structure and is searching for biomarkers for Parkinson's disease. She is a Fellow of the Royal Society of Chemistry and was awarded the 2009 Joseph Black award and the Theophilus Redwood Award from the RSC in 2019, Researcher of the Year 2020 from the University of Manchester and the ACS Measurement Science Lectureship 2021. In 2020 she initiated the COVID-19 Mass Spectrometry Coalition and was appointed as Chief Advisor to the UK Government on Mass Spectrometry as part of their pandemic response. Perdita has authored over 160 publications in peer reviewed journals. In 2021 Perdita founded the company Sebomix Ltd. to exploit sebum as a diagnostic biofluid with a focus on Parkinson’s Disease.

1. M. Spick, H‑M. Lewis, C.F. Frampas, K. Longman, C. Costa, A. Stewart, D. Dunn‑Walters, D. Greener, G. Evetts, M. J. Wilde, E. Sinclair, P.E. Barran, D.J. Skene, M.J. Bailey An integrated analysis and comparison of serum, saliva and sebum for COVID‑19 metabolomics, Sci. Rep. 2022, 12, 11867.
2. D.K. Trivedi, E. Sinclair, Y. Xu, D. Sarkar, C. Walton-Doyle, C. Liscio, P. Banks, J. Milne, M. Silverdale, T. Kunath, R. Goodacre, P. Barran Discovery of Volatile Biomarkers of Parkinson’s Disease from Sebum, ACS Cent. Sci. 2019, 5, 599-606.
3. R. Beveridge, L.G. Migas, R.K. Das, R.V. Pappu, R.W. Kriwacki, P.E. Barran Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins J. Am. Chem. Soc. 2019, 141, 4908-4918.

Organic Chemistry

Erick M. Carreira

ETH Zürich

Erick M. Carreira is a full Professor at the Organic Chemistry Laboratory of the ETH Zürich since 1998. He is the recipient of numerous awards, invited lectureships and prestigious positions including the Lieben Award (Austrian Chemical Society), Yamada Koga Prize (Japanese Chemical Society), American Chemical Society Award in Pure Chemistry, Nobel Laureate Signature Award, Fresenius Award, a David and Lucile Packard Foundation Fellowship in Science, Alfred P. Sloan Fellowship, Camille and Henry Dreyfus Teacher Scholar Award, Merck Young Investigator Award, Eli Lilly Young Investigator Award, Pfizer Research Award, National Science Foundation CAREER Award, Arnold and Mabel Beckman Young Investigator Award, the ACS Award for Creative Work in Synthetic Organic Chemistry, and a Camille and Henry Dreyfus New Faculty Award. In addition to being a member of the U.S. National Academy of Sciences and the American Academy of Arts and Sciences Prof. Carreira has also received several prestigious teaching awards and been involved in the development of chemistry education software packages. Regarding translational and industrial involvement, it should be noted that Prof. Carreira has co-founded of three start-up companies. In term of scientific publishing, in 2019, Prof. Carreira was appointed as the editor-in-chief of Organic Letters, after serving as an associate editor for 18 years, and as of 2021 was asked to serve as the editor-in-chief of the ACS flagship journal, The Journal of the American Chemical Society. With over 450 publications, Professor Carreira’s research program, which involves the asymmetric synthesis of stereochemically complex bioactive natural products, has significantly impacted the important scientific areas of synthetic and medicinal chemistry and applied chemical biology.

1. 1. M. J. Classen, M. N. A. Böcker, R. Roth, W. M. Amberg, E. M. Carreira Enantioselective Total Synthesis of (+)-Euphorikanin A, J. Am. Chem. Soc. 2021, 143, 8261–8265.
2. 2. M. Isomura, D. A. Petrone, E. M. Carreira Construction of Vicinal Quaternary Centers via Iridium-Catalyzed Asymmetric Allenylic Alkylation of Racemic Tertiary Alcohols , J. Am. Chem. Soc. 2021, 143, 3323–3329.
3. 3. K. M. Hugentobler, E. M. Carreira Discovery and Surprises with Cyclizations, Cycloadditions, Fragmentations, and Rearrangements in Complex Settings Acc. Chem. Res. 2021, 54, 890–902.

Young Chemists Choice

Kelly Chibale

University of Cape Town

Kelly Chibale obtained his PhD in Synthetic Organic Chemistry with Stuart Warren from the University of Cambridge, UK (1992), followed by postdoctoral fellowships at the University of Liverpool and Scripps Research Institute. He has held prestigious visiting positions at University of California San Francisco, University of Pennsylvania School of Medicine (Fulbright) and Pfizer, UK. As full Professor of Organic Chemistry at the University of Cape Town, he is the Neville Isdell Chairholder in African-centric Drug Discovery & Development, a Tier 1 NRF SARCHi South Africa Research Chair in Drug Discovery, founding Director of the extramural South African Medical Research Council Drug Discovery & Development Research Unit at UCT, Founder and Director of the UCT Drug Discovery and Development Centre, H3D and full member of the UCT Institute of Infectious Disease & Molecular Medicine. In terms of accolades, in 2018 Kelly was recognized by Fortune magazine as one of the “top 50 World's Greatest Leaders”, and in 2019 he was named as one of the “100 Most Influential Africans” by New African magazine. Subsequently, in 2020, he was named as one of the world’s top 60 most inspirational leaders in the pharmaceutical industry on the “Medicine Maker's 2020 Power List”. Kelly serves on several editorial advisory boards, including the ACS’s Accounts of Chemical Research and ACS Infectious Diseases, and is an Associate Editor of the Journal of Medicinal Chemistry. He has also been the recipient of the Gold Medal of the South African Chemical Institute (2018), the premier award of the Institute. His research focuses on African-based solutions for African disease challenges!

1. S. Winks, J. G. Woodland, G. Pillai, K. Chibale Fostering drug discovery and development in Africa, Nat. Med., 2022, 28, 1523.
2. V. Singh, K. Chibale Strategies to combat multi-drug resistance in tuberculosis, Acc. Chem. Res., 2021, 54, 2361.
3. L. P. Khonde, R. Müller, G. A. Boyle, V. Reddy, A. T. Nchinda, C. J. Eyermann, S. Fienberg, V. Singh, A. Myrick, E. Abay, M. Njoroge, N. Lawrence, Q. Su, T. G. Myers, H. I. M. Boshoff, C. E. Barry III, F. A. Sirgel, P. D. van Helden, L. M. Massoudi, G. T. Robertson, A. J. Lenaerts, G. S. Basarab, S. R. Ghorpade, K. Chibale 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis, J. Med. Chem. 2021, 64, 12790.

Physical Chemistry

Tomislav Friščić

University of Birmingham

Tomislav Friščić is currently a professor and Tier-1 Canada Research Chair in Mechanochemistry and Solid-state Chemistry at the Department of Chemistry, McGill University. In September 2022 he will take up the role of Leverhulme International Chair in Green and Sustainable Chemistry at the School of Chemistry at the University of Birmingham. He received his B.Sc. at the University of Zagreb with Branko Kaitner (2001), followed by a Ph.D. with Len MacGillivray at the University of Iowa (2006). He was a post-doctoral associate with William Jones (2006), a Herchel Smith Research Fellow at the University of Cambridge (2008), joining McGill University in 2011. His group is a team of excited and highly dynamic undergraduates, graduate students and post-doctoral scientists who work together to develop solid-state catalytic and self-assembly methodologies in diverse areas of organic, metal-organic, pharmaceutical and materials synthesis. He has co-authored >250 research and review articles, as well as book chapters, in the areas of solid-state and materials chemistry, Green Chemistry, crystal engineering and mechanochemistry. He is a co-founder of spin-off businesses Acsynam and Form-Tech Scientific, the Chair of the Canadian National Committee for Crystallography (CNCC), Fellow of the Royal Society of Chemistry, and a member of the Royal Society of Canada College of New Scholars, Artists and Scientists.

1. Do, J.-L. and Friščić, T Mechanochemistry: A Force of Synthesis, ACS Cent. Sci. 2017, 3, 1, 13-19.
2. Julien, P. A., Mottillo, C. and Friščić, T Metal–organic frameworks meet scalable and sustainable synthesis, Green Chem. 2017, 19, 2729-2747.
3. Lukin, S., Germann, L. S., Friščić, T and Halasz, I. Toward Mechanistic Understanding of Mechanochemical Reactions Using Real-Time In Situ Monitoring Acc. Chem. Res. 2022, 55, 9, 1262-1277.

Polymer Chemistry

Natalie
Stingelin

Georgia Institute of Technology

Natalie Stingelin is a Full Professor at the Georgia Institute of Technology and Chair of the School of School of Materials Science & Engineering. She is the Director of Georgia Tech’s Center of Organic Electronics and Photonics, and was elected a 2021 Fellow of the U.S. National Academy of Inventors, a 2019 Fellow of the Materials Research Society; and is a Fellow of the Royal Society of Chemistry since 2012. Her research interests encompass the broad area of functional polymer materials, polymer physics, organic electronics & photonics, and bioelectronics.

1. Nicolini, T., Surgailis, J., Savva, A., Scaccabarozzi, A. D., Nakar, R., Thuau, D., Wantz, G., Richter, L. J., Dautel, O., Hadziioannou, G., Stingelin, N. A Low-Swelling Polymeric Mixed Conductor Operating in Aqueous Electrolytes Adv. Mater., 2021, 33, 2005723.
2. Yu, L., Pavlica, E., Li, R., Zhong, Y., Silva, C., Bratina, G., Müller, C., Amassian, A., Stingelin, N. Conjugated Polymer Mesocrystals with Structural and Optoelectronic Coherence and Anisotropy in Three Dimensions. Adv. Mater. 2022, 34, 2103002.
3. Bachevillier, S., Yuan, H.K., Tetzner, K.Bradley, D. D.C., Anthopoulos, T. D., Stavrinou, P. N.,Stingelin, N. Planar refractive index patterning through microcontact photo-thermal annealing of a printable organic/inorganic hybrid material Mater. Horiz., 2022, 9, 411-416.

Inorganic Chemistry

Jan J.
Weigand

TU Dresden

Jan J. Weigand obtained his diploma in chemistry in 2002 and his Dr. rer nat. in 2005 from the LMU in Munich. He was awarded the Bavarian culture prize im 2005 and obtained a Lynen Scholarship from the AvH foundation for postdoctoral research at Dalhousie University in Halifax (Canada). He returned to Germany with a “Lynen Return Fellowship” and started his habilitation at the WWU Münster in 2007, under the supervision of Prof. Hahn. Shortly after, he was awarded the Liebig scholarship of the FCI which allowed him to start his independent career in 2008. In April 2010 he became fellow of the very prestigious Emmy Noether research program awarded by the DFG and obtained the Wöhler research award for young scientist. In July 2012, he also obtained from the EC (European council) an “ERC starting grant”. Since 2013, he is Professor at the TU University Dresden and is currently the Chair of Inorganic Molecular Chemistry. One of his main research interests is the development of new and sustainable synthesis routes to novel cationic and neutral phosphorus compounds and their use in synthetic applications of fundamental and industrial relevance. Furthermore, the group is involved in “solvent extractions”, novel recycling strategies and technical chemistry applications.

1. M. Donath, K. Schwedtmann, T. Schneider, F. Hennersdorf, A. Bauzá, A. Frontera, J. J. Weigand Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation Nat. Chem., 2022, 14, 384.
2. J. Wang, K. Schwedtmann, K. Liu, S. Schulz, J. Haberstroh, G. Schaper, A. Wenke, J. Naumann, T. Wenke, S. Wanke, J. J. Weigand Flowers of the plant genus Hypericum as versatile photoredox catalyst Green. Chem. 2021, 23, 881.
3. L. Götzke, G. Schaper, J. März, P. Kaden, N. Huittinen, T. Stumpf, K. K. K. Kammerlander, E. Brunner, P. Hahn, A. Mehnert, B. Kersting, T. Henle, L. F. Lindoy, G. Zanoni, J. J. Weigand Coordination chemistry of f-block metal ions with ligands bearing bio-relevant functional groups Coord. Chem. Rev., 2019, 386, 267.