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SACI News July 2017

                       

Later this week the SACI AGM will have taken place and the Institute will have a new President. Prof Martincigh has played a very important role as the SACI President for the past two years. She has led from the front and during her tenure she has moved the Society forwards in very positive ways. She will still maintain an active role on the Executive (as Past President) so her energy and enthusiasm will not be lost to the chemistry community.


This newsletter contains information on a number of new workshops and conferences. The important event to appear in 2020 – the International Conference on Chemical Education (ICCE) comes to SA!


Neil Coville

Content

  • SACI office address and times
  • Advertising in the SACI newsletter
  • Section and Divisions News
    Education Division
  • SACI North Section- Young Chemist Symposium
    Inorganic Division - INORG2017 report
  • IUPAC
    IUPAC General Assembly
  • African Journals of Chemistry
  • Funding opportunity
  • CAIA Newsletter
  • SACI and SACI related conference events
  • 2017 ChromSA Chromatography Postgraduate Student Seminar
    4th International Symposium on Electrochemistry
    Frontiers of Electron Microscopy in Materials Science (FEMMS) 2017
    AMRS2017 (Africa Materials Research Society)
    7th Mintek Analytical Sciences Symposium
    Atlantic Basin Conference on Chemistry
    The 3rd TCS International Conference and the 6th FASC Congress
  • Other conferences
  • Courses and Workshops
  • ChromSA and SAAMS GC-MS course 0
  • Positions available
    Post doc pSections_Divisionosition, UFS (organic chemistry)

SACI office address and times

The SACI office, run by Laila Smith is located on the 1st Floor of Gate House, room 124. The telephone number is 011 717 6705 and e-mail address is: saci.chem@wits.ac.za. The cel number is 061 282 3477.

This year we are to experiment with having Laila work in the afternoons from home. This will mean that office hours will be from 8.30 am till 1.00 pm. She can still be contacted at any time during her office hours. We have noted that there are very few members (or others) who physically visit the office at Wits.

Advertising in the SACI newsletter

The newsletter provides a means of getting messages to our membership. Currently the SACI membership stands at over 1000. This newsletter thus provides a means of advertising employment opportunities, conferences and workshops, and even for companies/Universities to promote themselves. We encourage members to use the Newsletter for advertising purposes. All SACI related conferences and events are advertised for free; if not a SACI related event there could be a small charge. For advertising costs contact Laila at the SACI office.       

Sections and Divisions news 

  • Chemical Education Division

Dear SACI Chemical Education members

I have just heard from Prof Marietjie Potgieter that our bid to host the ICCE conference in 2020 in Cape Town was successful! There were two bids to host the conference - ours and one of Thailand. The Thailand bid was very well prepared, but the committee accepted ours based on the perception that it will mean more to chemistry and science education in South Africa than to Thailand to host the conference.

Marietjie wrote: "South Africa, Cape Town in all its splendor and Nelson Mandela was a winning combination. Add to that the lovely visuals, good information and great assistance provided by the Western Cape Convention Bureau and voila! With such an appeal it would have sold itself - it did not need me at all."

However, I think she is being too modest, and I am sure you would all join me in thanking her for the good work she did in presenting our case. I would also like to congratulate Prof Bette Davidowitz for the work she did on putting the bid together.

I hope to see you all in Cape Town in 2020! 

Regards
Helen (Drummond)

  • SACI North Section- Young Chemist Symposium

         Download abstract template

  • Inorganic Division

The 18th SACI National Inorganic Chemistry Conference and Carman Physical Chemistry Symposium (Inorganic 2017) was held at the Arabella Hotel and Spa, Hermanus close to the town of Kleinmond in the Western Cape. It started on Sunday 25th June 2017 with a welcome mixer held in the hotel lounge and bar and ended with a closing ceremony immediately before lunch on Thursday 29th June.

The conference consisted of two full days and two half days and covered key aspects of modern inorganic and physical chemistry, including: bioinorganic chemistry; metal-organic frameworks and porous materials; reaction mechanisms; computational chemistry; structure and bonding; metals in medicine; catalysis; nanomaterials and nanotechnology; organometallic chemistry.

The programme included five plenary speakers who are prominent international experts. Titles of their 45 minute lectures are included after their names and affiliations:

D. Scott Bohle, Canadian Research Chair in Bioinorganic Chemistry, Department of Chemistry, McGill University, Montreal, Canada. New chemistry from ancient drugs: malaria pigment and the quinoline antimalarials.
Matthias Bickelhaupt, Department of Chemistry, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. Towards rational design of chemical reactions. Orde Q. Munro, DST-NRF SARChI Chair in Bioinorganic Chemistry, School of Chemistry, University of the Witwatersrand, Johannesburg, South Africa. Elucidating mechanisms of action in cytotoxic DNA-binding Au(III) and Cu(II) complexes.  Peter J. Sadler, Department of Chemistry, Warwick University, Warwick, United Kingdom. Design of precious metal anticancer and antimicrobial drugs for combatting resistance.  Karine Philippot, Laboratoire de Chimie de Coordination, CNRS, Toulouse, France. Synthesis of metal nanomaterials for catalysis inspired by molecular chemistry concepts.

One 45 minute SACI award lecture was presented:

2016 Gold Medallist of the South African Chemical Institute. Timothy J. Egan, Professor of Inorganic Chemistry, University of Cape Town. Exploring the fate of haem in the malaria parasite.

Ten 30 minute keynote lectures were given:

Susan A. Bourne, Department of Chemistry, University of Cape Town. Chromophoric framework solids for sensing and storage. Manuel A. Fernandes, School of Chemistry, University of the Witwatersrand. Molecular dynamics from slow diffraction experiments. Jeanet Conradie, Department of Chemistry, University of the Free State. Influence of the electronegativity of different beta-diketonato substituents on the reactivity of iron(III) beta-diketonato complexes. Kevin J. Naidoo, Department of Chemistry, University of Cape Town. Computational enzymology: virtually climbing hills and breaking through barriers to reveal reaction mechanisms. Jan Rijn Zeevaart, Radiochemistry, NECSA. Current application of radiometals in radiopharmacy. Stephen O. Ojwach, School of Chemistry and Physics, University of KwaZulu-Natal. Catalytic hydrogenation reactions of saturated substrates mediated by nitrogen-donor Fe(II), Ni(II) and Ru(II) complexes. Priscilla G. L. Baker, Department of Chemistry, University of the Western Cape. New materials for new frontiers –an electrochemical perspective. Nosipho Moloto, School of Chemistry, University of the Witwatersrand. Semiconductor nanocrystals as effective materials for nanoelectronics. Werner E. van Zyl, School of Chemistry and Physics, University of KwaZulu-Natal. Phosphor-1,1-dithiolate complexes: formation and application. Marile Landman, Department of Chemistry, University of Pretoria. CpM(NHC) (M = Cr, Ni, Ru) complexes: synthesis, electrochemistry, DFT studies and C-C and C-O catalytic applications.

In addition, there were 28 oral presentations of 20 minutes duration. Speakers were from: the University of the Witwatersrand; Vaal University of Technology; Durban University of Technology; Rhodes University; CSIR; Cape Peninsula University of Technology; NorthWest University (Mafikeng Campus); Nelson Mandela Metropolitan University; the University of Western Ontario, Canada; McGill University, Canada; the University of KwaZulu-Natal (Westville Campus); the University of Pretoria; Stellenbosch University; the University of KwaZulu-Natal (Pietermaritzburg Campus); the University of Fort Hare; NorthWest University (Potchefstroom Campus); the South African Agency for Science and Technology Advancement (SAASTA); the University of Johannesburg.
Eighteen posters, 17 of them student posters, were selected for 4 minute flash talks. These represented the following institutions: Durban University of Technology; Tshwane University of Technology; Stellenbosch University; the University of Johannesburg; the University of Cape Town; Nelson Mandela Metropolitan University; the University of Limpopo; the University of KwaZulu-Natal; the University of Zululand; North-West University; Cape Peninsula University of Technology; University of Pretoria.

Prizes for the best flash talks presented by MSc or PhD students were sponsored by the American Chemical Society through the journal Inorganic Chemistry. Three gold prizes to the value of R1500 were awarded and three silver prizes to the value of R500. The winners were as follows:

Gold Prizes:  Isabella Claassens (Stellenbosch University) - Solvent-dependent site-selective photochemical [2+2] cycloaddition in a cadmium MOF. Nicola Dare (University of Cape Town) - Using metal-organic frameworks to investigate iron(III)porphyrins.  Kudzanai Nyamayaro (Cape Peninsula University of Technology) - Dissolution control of highly soluble active pharmaceutical ingredients via co-crystallisation.

Silver Prizes:  Tendai Dembaremba (Nelson Mandela Metropolitan University) - Investigating oxovanadium(IV) complexes as potential catalysts for oxidative desulfurization. Daphney Makhafola (University of Limpopo) - Graphene oxide/metal organic framework nanocomposite as an effective electrocalyst for hydrogen evolution reaction. Chandre Sammy (Stellenbosch University) - Towards the development of new metallo-drugs to combat malaria.

Posters
In total 119 posters were presented and prizes were awarded to MSc and PhD student presenters. These were sponsored by the Royal Society of Chemistry, South Africa Southern Local Section. Three gold prizes to the value of R1500 each and three silver prizes to the value of R500 each were awarded. The winners were as follows:

Gold Prizes:  Ms W. Duminy (University of the Witwatersrand) - Design and synthesis of a Pd(II) chelate for targeting solvent-exposed histidine residues. Ms R Mohunlal (University of Cape Town) - An investigation into the biological molecules involved in haemozoin formation in the malaria parasite.  Ms K. Shunje (Cape Peninsula University of Technology) - Hydrogen bonding in selected cocrystals of sulfapyridine and sulfadiazine.

Silver Prizes:  Ms N. Baartzes (University of Cape Town) - Synthesis and antimicrobial evaluation of organometallic aminoquinoline-benzimidazole hybrids.  Ms S. Bhikraj (University of KwaZulu-Natal) - Gold(III) pseudomacrocyclic bis(pyrrolide-imine) Schiff base complexes: potential chemotherapeutic agents.  Mr T. Senapathi (University of Cape Town) - A study of the substrate selectivity of the human ST6Gal-I enzyme.

The conference was organised by a team of academics from the Cape Peninsula University of Technology, Stellenbosch University, University of Cape Town and the University of the Western Cape. The organising committee consisted of the following people: Dr Edith Antunes, UWC – scientific programme sub-committee Dr Nikoletta Bathori, CPUT – registration desk Dr Prinessa Chellan, SU – social programme and SACI liaison, abstract book Dr Katherine de Villiers – committee secretary Prof. Timothy Egan – chair Prof. Delia Haynes – coordinator of volunteers and session manager Dr Rehana Malgas-Enus – treasurer Dr Clive Oliver – scientific programme sub-committee Prof. Greg Smith – scientific programme sub-committee chair

A total of 180 delegates attended the conference. The vast majority of delegates were from South African institutions, with 11 (6%) from other countries. These were from Botswana (5), Cameroon (1), Canada (3), France (1) and the United Kingdom (1). South African delegates represented a wide range of academic institutions as well as the CSIR, NECSA and NRF.

Sponsorship was obtained from a considerable number of companies and entities. We are extremely grateful for their support. These comprised: the Department of Science and Technology of the Republic of South Africa; the South African Agency for Science and Technology Advancement (SAASTA); University of Cape Town; Bruker; PerkinElmer; Stellenbosch University; Devos Laboratory Consultants; Poretech; Sumaridge Wine Estate; Wirsam Scientific; University of the Western Cape; Anton Paar; Benguela Cove Lagoon Wine Estate; Bruno Steiner Lab Consultancy; Kimix; Labotec; United Scientific; Inorganic Chemistry; Royal Society of Chemistry, South Africa South, Local Section.

The sponsorship from the Department of Science of Technology was used to subvent student registration fees. Thanks in part to this student delegates made up 54% of the total conference attendees. The social programme consisted of a cocktail mixer on Sunday 25th June, a braai on Monday 26th June and a gala dinner on Thursday 28th June. All were held at the Arabella Hotel and Spa. The Tuesday afternoon excursion options were a wine tour followed by dinner at Hermanus Harbour Rock restaurant or a tour to Hermanus. These were for delegates own accounts. Affordable supper options were offered by the hotel for the benefit of students who remained at the Arabella on the free afternoon.

Feedback from delegates has been overwhelmingly positive.

Report by Prof Tim Egan

IUPAC

For the latest news see: http://www.saci.co.za/iupac.html


African Journals of Chemistry

  • South African Journal of Chemistry
  • This Journal is published electronically. The webpage is:  http://www.saci.co.za/ The South African Journal of Chemistry, published by the South African Chemical Institute, has been publishing high quality papers, in all fields of Chemistry for over 50 years. The Journal went fully electronic in 2000 and is freely available through open access online (http://reference.sabinet.co.za/sa_epublication/chem). It is a CAS-abstracted publication and is listed in Current Web Contents. It has retained its status as an accredited publication with the South African Department of Higher Education and Training.
  • African Journal of Chemical Education
    Enquiries and manuscripts should be addressed to the Editor-in-Chief: email eic@faschem.org, PO Box 2305, Addis Ababa, Ethiopia. AJCE, 2016, 6(1) ISSN 2227-5835 The online version appears in the FASC website (www.faschem.org) and in the AJOL website (www.ajol.info)

Funding opportunity

Subject: GCRF Global Engagement Meetings

Dear RCSG members,

The Global Challenges Research Fund (GCRF) is running a series of international Global Engagement Meetings.  The application form to attend the Meetings is now open and can be found at the link below.  Applications are open to UK and non-UK academics and non-academics that have an interest in international development research.  It would great if you could promote to your networks, particularly partners who may be interested in attending.

More details about the Meetings and application form can be found here: www.rcuk.ac.uk/funding/gcrf/gcrf-global-engagement-events and here http://www.smartsurvey.co.uk/s/XLN0E/

The aim of these large scale events is to showcase the opportunities available through the GCRF; to bring together developing country and UK researchers and representatives from other organisations to forge networks; and to discuss opportunities for maximising the contribution of GCRF research into policy and practice.

The Meetings will be held on the following dates and locations:
·       Colombia (Bogota) Wednesday 4th-Friday 6th October 2017
·       India (Delhi) Tuesday 7th-Thursday 9th November 2017
·       South Africa (Pretoria) Tuesday 5th-Wednesday 6th December 2017

Applications are open until Thursday 27th July, and successful applicants will hear in early August. Please circulate this to your contacts.

If you have any queries please contact gcrf@rcuk.ac.uk

Best wishes, Yaso
Yaso Kunaratnam
Research & Policy Officer, UKCDS

CAIA Newsletter

The latest issue of CAIA news is available. Go to:  http://www.caia.co.za/news/chemnews/
 or e-mail: caia@iafrica.com for pdf files of news and information.

SACI and SACI related Conference events

  • 2017 CHROMATOGRAPHY POSTGRADUATE STUDENT SEMINAR

Download registration form

  • 4th International Symposium on Electrochemistry

     

On behalf of ElectrochemSA, I cordially invite you to the 4th International Symposium on Electrochemistry.
Our theme for this conference is “Pure and Applied Electrochemistry”.

Electrochemistry, though traditionally a subset of physical chemistry and analytical chemistry, in recent times has emerged to be a notable branch of chemistry. Electrochemistry is applied in biochemistry, material science, biotechnology, nanotechnology, engineering, mining, environmental science, water treatment technologies, biomedicine, energy and so on. It is a key science behind many technologies such as sensors, biosensors, solar cells, batteries, capacitors, supercapacitors, fuel cells, hydrogen storage, water splitting, electroplating, corrosion, and many ‘green’ water treatment processes such as photoelectrochemical oxidation and electrocoagulation, among others.

The 4th Symposium on Electrochemistry is aimed at meeting the global challenges (especially in Africa) in water, biomedical, environmental, energy etc by bringing together electrochemists and other scientists/engineers whose integral part of their research involves electrochemistry. It will be a platform to share and update knowledge, stimulate new ideas, networking and collaborate. In addition, special attention will be given to students’ participations and interactions.

Prof. Omotayo A. Arotiba MRSC

Scope

  • Sensors and Biosensors
  • Photoelectrochemistry
  • Environmental Electrochemistry
  • Electrochemical Water Treatment Technologies
  • Electrochemistry of materials and nanomaterials
  • Electrochemistry for Energy
  • Electrocatalysis
  • Industrial Electrochemistry

Important deadlines

  • 20 July 2017: Submission of the abstracts
  • 4 August 2017 Abstract Submission closes
  • 10 August 2017: Information to authors about acceptance of abstracts
  • 12 – 20 August 2017: Early registration with reduced fee
  • October 12th-14th, 2017: Workshop
  • 15 November 2017: Conference begins

Venue and Accommodation

  • The School of Tourism and Hospitality, University of Johannesburg is an excellent environment for conferences and international cuisine.
  • Affordable accommodation will be provided for student.
  • More information on accommodations close to the venue will be provided in subsequent calls

Special Issue

  • Information will be provided

Web page

http://www.saci.co.za/ElecrochemSA/symposium_home.html

 

Dear Colleague,

On behalf of the Organizing Committee of FEMMS 2017, we would like to invite you to join us during this meeting. Poster submissions are open now  http://femms2017.org/submission.html

Deadline for poster abstract submissions as well as for the early-bird registration is 31. JULY, 2017.
Participants are invited to present outcomes of their research at FEMMS 2017 as poster presentations. Those interested need to submit an abstract by downloading and completing the template, then filling out the form to submit it. All poster abstracts that are accepted for presentation will be published in the conference booklet.             
FEMMS is a biennial meeting focused on the application of electron microscopy, primarily TEM, in materials science. The conference series primarily arose to satisfy the requirements of the electron microscopy community working on materials science problems, which grew explosively in the late 1980’s and has expanded to include researchers working with analytical periphery, novel instrumentation, tomography, operando and correlative microscopy, and advancing into the domain of ultrafast time-resolved microscopy. 

Traditionally, FEMMS brings together approx. 40 invited speakers plus one distinguished lecturer - all confirmed and listed below -  that are world-renowned experts, principal investigators and project leaders, to present their latest advances in the field of electron microscopy in the materials sciences.

FEMMS 2017 will be held in at the Indaba Hotel & Conference Center in Fourways, Johannesburg,
Submissions for student posters will open in mid June 2017.

We are confident that FEMMS 2017 will be a great and successful meeting.
We look forward to your active support and participation.

Sincerely yours,

Alexander Ziegler
femms2017@gmail.com; http://femms2017.org/

 

  • AMRS2017 (Africa Materials Research Society)

           

  • Atlantic Basin Conference on Chemistry

                               


ABCChem – Plenary Speakers Announced!
ACS is partnering with societies in North and South America, Europe, and Africa for the first Atlantic Basin Conference on Chemistry (ABCChem) to be held in January 23–26, 2018, in sunny Cancún, Mexico.  A dynamic lineup of plenary speakers from across the region have been confirmed and will cover a range of topics including Chemistry in Biology, Green Chemistry, Materials & Nano Chemistry, and Physical & Analytical Chemistry.

Call For Papers – Submit Yours Today

The ABCChem Technical Programming Committee invites chemistry professionals across the regions to give oral and poster presentations on the topics listed above.  The deadline to submit abstracts is Monday, September 18, 2017.

Submit your papers and register now!  To ensure international collaboration, registration is limited by region.  Make sure to register early to secure your spot!

  • The 3rd TCS International Conference and the 6th FASC Congress

                                 

The conference will be held at the Arusha International Conference Center (AICC) in Arusha. Arusha city is exactly half-way between Cape Town and Cairo, only a stone’s throw away from Africa’s highest Mountain, Mt. Kilimanjaro and the safari-gateway to the astounding wildlife of Ngorongoro Crater, the Serengeti, Tarangire and Lake Manyara National Parks.

SYMPOSIUM THEMES


The conference will cover all areas of chemistry including but not limited to:
 Analytical Chemistry
 Physical Chemistry
 Inorganic Chemistry
 Organic Chemistry
 Natural Products Chemistry
 Environmental Chemistry
 Industrial Chemistry
 Forensic Chemistry
 Nanochemistry

Please register and make your submission at the following link:
http://www.tcs-tz.org/tcs-fasc2017

Or contact:

 

 

Prof. Othman C. Othman
+255 22 2410038
+255 713 433982
o_chande@yahoo.co.uk
ocothman@gmail.com
Chemistry Department
College of Natural and Applied Sciences
University of Dar es Salaam
P.O. Box 35061
Dar es Salaam, Tanzania

Dr. Clarence A. Mgina
+255 22 2410038
+255 767 547970
cmgina@yahoo.com
cmgina@udsm.ac.tz
Chemistry Department
College of Natural and Applied Sciences
University of Dar es Salaam
P.O. Box 35061
Dar es Salaam, Tanzania

Dr. Clarence A. Mgina
+255 22 2410038
+255 767 547970
cmgina@yahoo.com
cmgina@udsm.ac.tz
Chemistry Department
College of Natural and Applied Sciences
University of Dar es Salaam
P.O. Box 35061
Dar es Salaam, Tanzania

 

   

 

   

 

 

 

 Theoretical Chemistry
 Biochemistry
 Computational Chemistry
 Combinatorial Chemistry
 Chemical Education
 Green Chemistry
 Organometallic Chemistry
 Fuel Chemistry
 Medicinal Chemistry

  • 7th Mintek Analytical Sciences Symposium

               

                                                          

Others            

  • Lab Africa Conference and Exhibition, 15 – 17 August 2017; Ticketpro Dome, Johannesburg www.labafrica.co.za ;Tel: 011 011 9073; Info@labafrica.co.za
  • First Atlantic Basin Conference on Chemistry (ABCChem) – 24-26 January, 2018; Cancún, Mexico http://abcchem.org/about/societies/
  • The 3rd TCS International Conference and the 6th FASC Congress, Chemistry for Sustainable Development and Improved Livelihood  Arusha, Tanzania http://tcs-tz.org/tcs-fasc2017/
  • International Conference on Chemical Education 18, July 10-14 2018, Sydney
  • ACRICE-3 Algeria October. The website is www.univ-setif.dz/OCS/FT/ACRICE. The conference is under the aegis of IUPAC and FASC
  • Science Forum South Africa 7-8 Dec 2017, CSIR International Convention Centre, Pretoria
  • African Materials Research Society (AMRS) Conference 2017, 11-14 Dec 2017, Gaborone, Botswana. www.amrsbotswana.org
  • 7th SANi-NYRS symposium
    The South African Nanotechnology Initiative (SANi) together with Tshwane University of Technology (TUT) are excited to announce the coming 7th SANi-NYRS symposium hosted at Tshwane University of Technology (TUT) in Pretoria west, TUT main campus, on the 20th of October 2017 under the theme “Nanotechnology For The 21st Century Challenges”. Thus, we will appreciate it extensively if the attached announcement can be circulated to various Departments within your Institution and also be posted on the notice boards where students and interested candidates will clearly see it.
    Katlego Makgopa (PhD)
    Building 3, Office 614D
    Department of Chemistry
    Acardia Campus, 175 Mandela Drive
    Tshwane University of Technology 
    Tel: 0123826406;  0769932734
    Email: MakgopaK@tut.ac.za

Courses and Workshops

ChromSA and SAAMS will host a GC-MS course, presented by Dr Peter Gorst-Allman on Wednesday 23 and Thursday 24 August 2017 at the Willows Country Lodge in Lynnwood, Pretoria.

The objective of this GC-MS course is to teach analysts and students in practice how to use the systems correctly, how to develop methods successfully, and how to understand and interpret results. This will be achieved through a better understanding of how the instruments work, their strengths and limitations, and the basic fundamentals of the techniques. It is aimed at relatively inexperienced users to develop their skills and understanding, and at more experienced users who want a better knowledge of the instruments they use. This will be handled in depth in a simple and easy to understand set of presentations.

This workshop is an excellent opportunity for everyone working in the field of gas chromatography and mass spectrometry to strengthen their knowledge in this field by learning from an expert, Dr Peter Gorst-Allman.
For more Information and Registration – please go to https://carlamani.co.za/events/2017/gc-ms/
Administration will be handled by Carlamani Conferences and Events
We look forward to receiving your registrations.

Kind Regards
Carla de Jager
On behalf of ChromSA and SAAMS

Positions available

Post-doctoral candidate - organic synthesis and natural product chemistry (University of the Free State)

Job description
The Organic chemistry group within the Department of Chemistry (University of the Free State, South Africa) is looking for a Post-doctoral candidate interested in organic synthesis and natural product chemistry.
Our research is mainly based on natural phytomedicines and development of phytomedicines. We have collaborations with the University of Vienna and Basel on the development of anti-psychotic phytomedicines. We are also involved in the investigation of the sulfitation reactions of procyanidin dimers, trimers and tetramers based on catechin, epicatechin, gallocatechin and epigallocatechin flavan-3-ols.

We will soon be implementing HPLC-based profiling using a larval zebrafish seizure model induced by pentylenetetrazol (PTZ), a pro-convulsant GABAA receptor antagonist. The assay was validated with the aid of compounds with known GABAergic activity (diazepam, valerenic acid, magnolol and piperine, and additional GABAA receptor agonistic compounds that were previously identified with the aid of the Xenopus oocyte assay). We would like to establish a toxicity and activity testing centre for South African botanicals based on traditional knowledge which show the potential to be developed into possible lead compounds against diseases of the central nervous system (CNS) such as epilepsy, mood disorder, anxiety and insomnia.

Desired skills and experience
We are looking for a highly motivated and enthusiastic candidate with a background in organic chemistry, natural product chemistry or related fields with an interest in isolation and structure elucidation of natural/chemical compounds. Previous experience in synthetic chemistry, natural products and phytochemistry is desired. The candidate must be highly skilled in NMR, HPLC/MS/LCMS techniques with ample experience and a recognizable supervision track record with good communication in English (spoken and written). The candidate will be in charge of the HPLC equipment and should be available to provide training and support to post-graduate students regarding HPLC method development.

About the employer
The Organic chemistry group at the University of the Free State is well equipped with the following NMR equipment: 300 MHz NMR with a 5 mm broad-band probe, 300 MHz NMR with a 5 mm 1H and 13C dual probe, 400 MHz NMR with a 5 mm broad-band probe, 10 mm broad-band probe and a 4 mm solid-state probe, 600 MHz NMR with a 5 mm 1H & 13C dual probe, a 5 mm broad-band probe and a 1.7 mm nano probe. Our laboratory has highly specialized equipment ranging from HPLC, MS, LCMS, countercurrent chromatography, GCMS etc. The research group is housed in the Department of Chemistry and offers close working relationships with other research groups in Physics, Microbiology, Biochemistry and Genetics.

How do you want candidates to apply?

E-mail address: wilhelma@ufs.ac.za

Which disciplines does your ideal candidate come from?
Chemistry – organic synthesis, natural product chemistry, phytochemistry, green chemistry